4-(3,3-Dimethylperhydro-1,3-oxazolo[3,4-a]pyridin-1-yl)-2,8-bis(trifluoromethyl)quinoline
نویسندگان
چکیده
An L-shaped conformation is found in the title mol-ecule, C(20)H(20)F(6)N(2)O, the C-C-C-C torsion angle linking the two fused-ring systems being -92.80 (19)°. The oxazole ring adopts an envelope conformation [the N atom lies 0.579 (2) Å out of the plane defined by the remaining atoms], and the piperidine ring has a chair conformation. Supra-molecular chains are found in the crystal structure that are sustained by C-H⋯π and π-π [3.6089 (10) Å] inter-actions.
منابع مشابه
3,4-Dimethoxybenzaldehyde [2,8-bis(trifluoromethyl)quinolin-4-yl]hydrazone
In the title compound, C(20)H(15)F(6)N(3)O(2), the quinoline ring system is almost coplanar with the benzene ring; the dihedral angle between the two planes is 2.31 (8)°. The crystal structure displays an inter-molecular C-H⋯F hydrogen bond. In addition, a weak π-π inter-action is observed between the unfused benzene ring and the benzene ring of quinoline, with a centroid-centroid distance of 3...
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In the title compound, C23H15F3N2O2S, the thia-zole ring makes dihedral angles of 12.98 (13), 49.30 (11) and 49.83 (12)° with the pyridine ring, the meth-oxy-phenyl ring and the (tri-fluoro-meth-yl)phenyl ring, respectively. In the crystal, mol-ecules are connected via C-H⋯O hydrogen bonds, forming chains along [010]. There are also C-H⋯π and C-F⋯π inter-actions present, forming a three-dimensi...
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عنوان ژورنال:
دوره 66 شماره
صفحات -
تاریخ انتشار 2010